Jayden
Seay
Reframing the Language of Time: The Master-Slave Clock
Abstract profile. Full document pending author claim.
Authors:
Jayden Seay, Hannah Marcus, Evelynn Hammonds
Date Created:
2025-01-01
Course Title:
Professor:
Not specified
About Paper:
The Harvard University Collection of Historical Scientific metaphor was known by those ‘behind the scenes,’ yet most Instruments (CHSI) displays a prominent example of the Shortt visitors, researchers, and Harvard community members did not Free Pendulum Regulator Clock No. 17 and Synchronome gain any insight into the nuances of this object or its relation to Feedback Clock in its Putnam Gallery. The Shortt Clock, the broader landscape of the legacy of enslavement at Harvard and built around 1929 and purchased for the use of the Institute beyond. Through archival research in the CHSI Object Files and of Geographical Exploration, was the subject of a 1957 rescue those of peer collections, paired with analysis and application of mission, after falling into disrepair following an earthquake and the 2007 article “Broken Metaphor: The Master-Slave Analogy in being left behind when the institute closed in 1952. The object Technical Literature”, the seminal text on the subject written by label which described the piece from 2005 until recently labeled ethnomathematician Ron Eglash, this report synthesizes primary the clock as a “Master and Slave Clock.” Although this metaphor and secondary sources in order to reinterpret the object on display has been used throughout the existence of the clock, the CHSI and create new interpretive signage. This project is a necessary label uses this metaphor to a greater extent than peer collections steptowardthegoalofrectifyingHarvard’slong-lastinglegaciesof and neglects to discuss the complicated language used to describe enslavement and actingon the university mottoof seeking ‘veritas’ the objects. The history of this object and the accompanying — the truth. Evaluation of Immunogenicity of Prefusion MERS Spike Nanoparticle Vaccines Gabriel Thomas, Sydney Moak, Kizzmekia S. Corbett-Helaire Delaware State University | Chemistry | 2026 MiddleEastRespiratorySyndromecoronavirus(MERS-CoV)first were immunized with 1▯g of vaccine with two doses spaced three emerged in 2012 in the Middle East, and as recently as April 2025, weeks apart. We then collected sera two weeks following the MERScaseswerereportedinSaudiArabia. Asahighlypathogenic second dose. We utilized Enzyme-linked immunosorbent assays virus with zoonotic transmission from dromedary camels, MERS- (ELISAs) to assess antibodies in the mouse sera that bind to CoV, causes severe respiratory disease with a ~36% case fatality MERS-CoV S-2P proteins from the various MERS-CoV strains. rate. Currently, there are no approved MERS-CoV vaccines Also, we implemented pseudovirus neutralization assays, using or therapeutics; as an imminent threat of a future MERS-CoV DPP4-expressing Huh7.5 cells, to assess the ability of those pandemic, vaccine development is ever so critical. serum antibodies to block MERS-CoVs from entering cells — effectively neutralizing the virus. All statistical analyses were MERS-CoV infection is mediated by the surface spike (S) performed using Graphpad PRISM software. Our rationally protein, comprising S1 (head) and S2 (stem) subunits. Infection is facilitated by the surface spike (S) protein binding to the designed NPs demonstrated stronger S-binding antibody responses cellular receptor dipeptidyl peptidase-4 (DPP4). We have recently and neutralization capacity compared to S-2P alone. This work designed nanoparticle (NP) protein vaccines, displaying perfusion provides a foundation for advancement of our S-2P NPs as MERS-CoV-specific vaccine candidates. Future work will involve stabilized MERS spike protein (MERS S-2P) using novel linkers pushing the boundaries of antibody breadth elicited by these (L2 and L6). Here, we evaluated immune responses to various vaccines towards pandemic preparedness. MERS-CoV strains (EMC 2012, England 1 and maMc34). Mice MethodologicalReviewofBehavioralHealthIntegrationStudiesinMedicaid:
Abstract:
The Harvard University Collection of Historical Scientific metaphor was known by those ‘behind the scenes,’ yet most Instruments (CHSI) displays a prominent example of the Shortt visitors, researchers, and Harvard community members did not Free Pendulum Regulator Clock No. 17 and Synchronome gain any insight into the nuances of this object or its relation to Feedback Clock in its Putnam Gallery. The Shortt Clock, the broader landscape of the legacy of enslavement at Harvard and built around 1929 and purchased for the use of the Institute beyond. Through archival research in the CHSI Object Files and of Geographical Exploration, was the subject of a 1957 rescue those of peer collections, paired with analysis and application of mission, after falling into disrepair following an earthquake and the 2007 article “Broken Metaphor: The Master-Slave Analogy in being left behind when the institute closed in 1952. The object Technical Literature”, the seminal text on the subject written by label which described the piece from 2005 until recently labeled ethnomathematician Ron Eglash, this report synthesizes primary the clock as a “Master and Slave Clock.” Although this metaphor and secondary sources in order to reinterpret the object on display has been used throughout the existence of the clock, the CHSI and create new interpretive signage. This project is a necessary label uses this metaphor to a greater extent than peer collections steptowardthegoalofrectifyingHarvard’slong-lastinglegaciesof and neglects to discuss the complicated language used to describe enslavement and actingon the university mottoof seeking ‘veritas’ the objects. The history of this object and the accompanying — the truth. Evaluation of Immunogenicity of Prefusion MERS Spike Nanoparticle Vaccines Gabriel Thomas, Sydney Moak, Kizzmekia S. Corbett-Helaire Delaware State University | Chemistry | 2026 MiddleEastRespiratorySyndromecoronavirus(MERS-CoV)first were immunized with 1▯g of vaccine with two doses spaced three emerged in 2012 in the Middle East, and as recently as April 2025, weeks apart. We then collected sera two weeks following the MERScaseswerereportedinSaudiArabia. Asahighlypathogenic second dose. We utilized Enzyme-linked immunosorbent assays virus with zoonotic transmission from dromedary camels, MERS- (ELISAs) to assess antibodies in the mouse sera that bind to CoV, causes severe respiratory disease with a ~36% case fatality MERS-CoV S-2P proteins from the various MERS-CoV strains. rate. Currently, there are no approved MERS-CoV vaccines Also, we implemented pseudovirus neutralization assays, using or therapeutics; as an imminent threat of a future MERS-CoV DPP4-expressing Huh7.5 cells, to assess the ability of those pandemic, vaccine development is ever so critical. serum antibodies to block MERS-CoVs from entering cells — effectively neutralizing the virus. All statistical analyses were MERS-CoV infection is mediated by the surface spike (S) performed using Graphpad PRISM software. Our rationally protein, comprising S1 (head) and S2 (stem) subunits. Infection is facilitated by the surface spike (S) protein binding to the designed NPs demonstrated stronger S-binding antibody responses cellular receptor dipeptidyl peptidase-4 (DPP4). We have recently and neutralization capacity compared to S-2P alone. This work designed nanoparticle (NP) protein vaccines, displaying perfusion provides a foundation for advancement of our S-2P NPs as MERS-CoV-specific vaccine candidates. Future work will involve stabilized MERS spike protein (MERS S-2P) using novel linkers pushing the boundaries of antibody breadth elicited by these (L2 and L6). Here, we evaluated immune responses to various vaccines towards pandemic preparedness. MERS-CoV strains (EMC 2012, England 1 and maMc34). Mice MethodologicalReviewofBehavioralHealthIntegrationStudiesinMedicaid:
Source:
Harvard / Howard University | Educational Studies | 2026 / 2025
Topics:
mers, clock, vaccine, object, protein, university, metaphor, spike, antibody, master, collection, chsi
