Thy
Pham
Sponsor: Oanh Meyer, Ph.D. MED: Neurology Studies have shown the importance of neighborhood factors, such as residential segregation and green space, in associations with older adult brain health. In this qualitative study, we examine older adults' perceptions of their neighborhood, with a particular focus on residential diversity and segregation. We recruited participants from the longitudinal cohort at the UC Davis Alzheimer's Disease Research Center to participate in semi- structured interviews. Participants were interviewed about features of their neighborhood and perceptions of their neighborhood. On average, individual interviews lasted 23 minutes, and were audiotaped, transcribed verbatim, and analyzed for recurring themes. A total of 26 participants were interviewed: 61.5% female, 50.0% non-Hispanic White and 50.0% Black/African American, mean age= 81.12, SD = 6.93 years. The most prominent themes were (1) Importance of public stores and similar third spaces; (2) Accessibility to green space (3) Staying active in the community, both physically and socially; (4) Neighborhood awareness and cohesion; and (5) Stereotypes, discrimination, and segregation. These findings highlight the social and built environment factors that are important to older adults and that may potentially affect brain health. Future research should examine how salient themes might differ depending on older adults' cognition. A Novel Method of Drosophila Sleep Tracking via AI-Driven Temperature Analysis
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Thy Pham
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Sleep is a biological mechanism heavily influenced by the circadian clock and is vital for homeostasis. Our research aims to build upon previous sleep studies and introduce a new method of tracking sleep via temperature to illustrate the circadian mechanisms responsible for sleep. Given that Drosophila relies on the environment for temperature regulation, a temperature gradient, and AI tracking assay was conducted over a 2-day (12H:12H) light/dark cycle to track sleep patterns. Analysis was performed using proprietary software to compare locomotor activity and body temperature rhythms (BTR). Wild-type (W1118 and CS) Drosophila lines were controls for general sleep patterns compared to Per, Tim, and Clock gene mutants. Results demonstrate that W1118 had a robust sleep pattern with average sleep bouts at their greatest during ZT16 to 17 before decreasing as the light phase began. This contrasted our mutant lines, which displayed inconsistent but similar sleep durations throughout the dark cycle. These results corroborate past studies on Drosophila circadian rhythms, revealing the circadian clock's role in sleep regulation and illustrating that our software is a valid tool for tracking sleep. The insights gained from Drosophila can elucidate sleep mechanisms and potential implications for sleep-related disorders. UC Davis 36 th Annual Undergraduate Research, Scholarship and Creative Activities Conference 222 Meaningful Photos: Exploring the Effects of Reflective Photo-Taking on Contentment, Gratitude, Stress Levels and Overall Life Satisfaction Tim Pham
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UC Davis / Neuro Physio & Behavior / 2025
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Thy Pham