Sponsor: M elizabeth Marder, Ph.D. Environmental Toxicology Infertility is a prevalent health challenge and evidence suggests that at least some fertility issues are associated with exposure to increasingly pervasive environmental toxicants. To minimize the risk from such exposures, medical professionals recommend making simple, proven lifestyle changes. Meanwhile, the wellness industry have begun to market preconception "detox" or "cleansing" supplements as a purported answer to the problem. We reviewed a range of such products available for sale in the United States and found that many of them appear to be herbal formulations marketed as alternative healthcare methods such as Ayurveda. Some active ingredients in these supplements may pose toxicity concerns and it is already well-established that such products can contain harmful amounts of toxic metals such as lead and mercury. To assess health risk, metal contaminants of concern were identified, followed by an assessment of dietary exposure using relevant concentration data. Next, standard approaches in health risk assessment were used to project the blood levels of metals of concern. These estimates, in conjunction with established health guidance values, were used to assess the potential risk that preconception "detox" supplements might pose to a concerned demographic of future parents. The Effects of Low Income Affordable Housing Tax Credit Development on Neighborhood Rent Burdens

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