Authors:

Sara Rottink

Date Created:

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About Paper:

Database for Standardized Clinical Care The clinical presentation of pediatric traumatic brain injury (pTBI) exhibits significant variability, contingent upon the age, severity, mechanism of injury, and location of the head trauma, among other factors. pTBI is a heterogeneous condition characterized by several modes of injury and a range of mechanisms by which neuronal damage may occur and represents a significant health burden for pediatric mortality and morbidity. To date, data remains elusive for factors that improve prognostication for said mortality and morbidity. This prospective, observational study aims to establish a comprehensive, multidisciplinary web-based database dedicated to pTBI, including standardized clinical information with neuroimaging, neurocognitive outcomes via GOS-E peds scoring, and a bio-sample repository. Taken together, this data will serve as a platform for a systemic, multimodal evaluation of pTBI severity and outcomes in comparison to a multitude of factors that can be extracted from the database to better standardize clinical care and promote accurate neurocognitive outcome prognostication. 78 patients have been enrolled with data collected via blood sampling, chart review, and follow up calls or appointments for neurocognitive evaluations. 255

Source:

University of Florida / 2024

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Co-authors:

Sara Rottink