Authors:

Ada Liu

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About Paper:

Human milk contains critical nutrients as well as a diverse microbiota that support growth and immune development for infants. The microbiota in human milk is a source of commensal bacteria for the infant which aid in metabolism and protection against pathogens. However, these commensals can also be a reservoir for antibiotic resistance genes (ARGs). Infants have a vast array of ARGs in their gut microbiota from mom's milk. The goal of this study is to identify antibiotic- resistant bacteria and determine the magnitude of their resistance. In our study, we isolated 91 bacterial strains from human milk and characterize the antimicrobial resistance profile. Antibiotic susceptibility tests revealed that most of the isolates were susceptible to ciprofloxacin and gentamicin, while up to 79% showed resistance to others, including ampicillin and vancomycin. Staphylococcus and Klebsiella were the most common bacteria found. Notably, 23% of strains were resistant to up to 3 antibiotics, 45% were resistant to 4 to 7 antibiotics, and 32% were resistant to more than 8 antibiotics. Acinetobacter defluvii emerged as a prevalent multi-drug resistant strain. These results highlight the critical need for monitoring the presence of microorganisms carrying out antibiotic resistance in the human milk microbiome to safeguard infant health. 279

Source:

University of Florida / 2024

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Co-authors:

Ada Liu