Authors:

Anna Riccardi

Date Created:

Not specified

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About Paper:

Precision medicine approaches hold promise for improving diabetes care globally, with monogenic diabetes serving as a key example. However, existing inequities in precision diabetes care risk exacerbating healthcare disparities. While underrepresentation of minority racial and ethnic groups in monogenic diabetes research has been documented, less is known about representation across educational and socioeconomic strata. This study examines Area Deprivation Index (ADI) — a measure of neighborhood-level disadvantage — and provider type as indicators of health literacy, socioeconomic status, and healthcare access among the University of Chicago Monogenic Diabetes Registry participants. We conducted a cross-sectional analysis of Registry participants, calculating ADI for each individual. Descriptive statistics were analyzed using R, with Wilcoxon and Kruskal-Wallis tests used for comparisons. Preliminary analysis demonstrated that Registry participants had a median US ADI of 32, significantly below the expected median of 50 (p<0.001), with only 27% residing in neighborhoods above the 50th percentile for deprivation. Preliminary data also showed higher rates of specialty care among participants compared to the general diabetes population and that provider-referred participants have a higher median ADI than self-referred participants, reflecting differential access patterns across the lifespan. These results suggest substantial national inequities in monogenic diabetes diagnosis, with individuals from disadvantaged neighborhoods and those without specialist access being underrepresented. These results highlight the critical need for targeted efforts to reach disadvantaged populations and ensure equitable access to the benefits of precision diabetes medicine.

Source:

University of Chicago

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No topics listed

Co-authors:

Anna Riccardi