Diya
Sakhrani

SURF Quantification of intervertebral disc strain from high-resolution ultrasound imaging during dynamic loading

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Authors:

Diya Sakhrani

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Lower back pain burdens two-thirds of people, with herniated discs commonly occurring in 20- 40-year-old patients. A healthy intervertebral disc (IVD) has an increased pressure measured inside the nucleus pulposus when experiencing an applied load, which then causes tension in the fibers of the annulus fibrosis. The mechanics leading to annular tears, which contribute to the high occurrence of herniated discs, remain insufficiently understood. This highlights the urgent need for research into the mechanisms of disc herniation to better understand the progression of this condition. Bovine caudal spine segments were prepared to isolate the IVDs by removing surrounding tissue and creating bone-disc-bone (BDB) segments by making cuts along the mid?transverse plane of the spine. The ends of the BDB segments were potted in polymethyl methacrylate and then an axial compression was applied to the samples using a custom-built testing device. Through the analysis of 2-dimensional direct deformation estimation, this study expects to see an estimated axial IVD strain with high frequency ultrasound. The IVD curvature is expected to increase as well as the strain with the increased axial compression of the IVD. This strain assessment will aid in the existing knowledge of IVD mechanical behavior with the goal to integrate advanced high-resolution ultrasound imaging and texture correlation techniques to accurately measure strain profiles within the IVD under dynamic loading conditions.

Source:

Purdue University / 2023

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Co-authors:

Diya Sakhrani

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