Authors:

Brielle Lowther

Date Created:

Not specified

Course Title:

Professor:

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About Paper:

Introduction: Individuals with problematic substance use and/or substance use disorders, especially people who inject drugs (PWID) are at increased risk for human immunodeficiency virus (HIV). Further, individuals engaging in problematic substance use may have poorer adherence to antiretroviral (ARV) medications that are used to both prevent and treat HIV. Objectives: The purpose of this literature review was to examine studies that evaluated behavioral interventions to enhance ARV medication adherence in samples of HIV-infected individuals or individuals at risk for HIV. Methods: Utilizing PRISMA guidelines for systematic reviews, searches of PubMed and electronic databases were used. Studies were included in the review if they: (a) reported outcomes from a behavioral intervention to enhance ARV adherence; and (b) included a sample of either HIV-infected or at-risk individuals engaging in problematic substance use. Results: The review included 28 articles. The methodology employed across studies was summarized; around 25% of studies used cognitive behavioral therapy, 14% used modified ART interventions, 11% used motivational interviewing, and 50% used other intervention approaches. Overall, cognitive behavioral therapy was the most effective intervention in enhancing ARV medication adherence compared to other modalities. Discussion: We examined the most common interventions and methods used in targeting HIV medication adherence. Cognitive behavioral therapy showed promise for enhancing ARV adherence rates. In conclusion, there is a need for further research on interventions increasing adherence that are feasible to administer among HIV-infected and at-risk individuals using substances.

Source:

Purdue University / 2023

Topics:

No topics listed

Co-authors:

Brielle Lowther