Authors:

Phuong Ba

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Introduction Coronary artery disease remains a leading cause of death worldwide, primarily due to atherosclerotic lesions that restrict myocardial perfusion. The right coronary artery (RCA) is the second most affected vessel, and lesion location within it may influence the degree of stenosis and clinical outcomes. Understanding this relationship may aid in early risk stratification, treatment planning, and complication prevention. This study evaluates whether a statistically significant association exists between RCA lesion location and stenosis severity using dynamic coronary angiography. Method A cross-sectional review was conducted on coronary angiograms from 30 patients presenting with unstable angina. Patients with a history of coronary artery bypass grafting or percutaneous coronary intervention were excluded. Lesions were categorized into four anatomical locations: 1R (mid-segment, proximal), 2R (mid-segment, distal), 3R (distal), and 4R (proximal). Lesions involving multiple sites were considered diffuse. Severity was classified as: no lesion (0%), mild (1-24%), mild-moderate (25-49%), moderate (50-69%), and severe (70-90%). A Chi-square analysis was used to evaluate the association between lesion location and severity. Result A significant association was found between RCA lesion location and severity (Chi-Square = 30.694, p = 0.002). Lesions in the 1R segment most frequently showed higher severity, with 25% classified as moderate and 25% as severe. In contrast, 2R and 4R lesions were exclusively mild, while diffuse lesions were associated only with moderate severity. Conclusion † Presenting Undergrad Author; ‡ Contributing Undergrad Author; * Undergrad Acknowledgment 1R lesions are most prone to severe stenosis, while 2R, 4R and diffuse lesions tend to be milder, possibly reflecting early multi-vessel disease. Identifying high-risk RCA segments may enable earlier, targeted interventions. Keywords: Right Coronary Artery; Atherosclerotic Lesions; Myocardial Perfusion; Dynamic Coronary Angiography; Stenosis

Source:

Purdue University / 2025

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Co-authors:

Phuong Ba