Authors:

Cao Danh Vo

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Background: Vietnam has experienced remarkable socioeconomic growth, with GDP rising from $31.2 billion (2000) to $410 billion (2022), and life expectancy reaching 75 years. However, the Healthy Life Expectancy (HALE) remains at 65.4 years, with ischemic heart disease and diabetes now ranked second and fifth, respectively, among leading causes of death. Concurrently, obesity is rising, with adult BMI ?30 kg/m² increasing from 0.3% (2000) to 2.02% (2021). These trends present new challenges in managing acute coronary syndrome (ACS), particularly in elderly patients with comorbidities. This study aimed to compare clinical outcomes of myocardial infarction (MI) in elderly patients by BMI status. Methods: A prospective study was conducted from June to December 2023 on patients aged ?65 years diagnosed with MI. Patients were evaluated based on 2021 AHA/ACC/ASE/SCMR guidelines. Data collected included demographics, clinical history, comorbidities, ACS type (STEMI/Non-STEMI), revascularization strategy, echocardiographic findings, and discharge prescriptions. Patients were stratified into normal BMI (18.5 - 24.9) and overweight (?25) groups. Results: A total of 135 patients (mean age 74.0 ± 7.4 years; 52 males) were included. STEMI occurred in 71 patients, and 117 underwent PCI. The overweight group had significantly shorter hospital stays (7.4 ± 5.0 vs. 9.3 ± 4.5 days; p = 0.023) but lower LVEF (49.4 ± 13.5% vs. 54.5 ± 12.5%; p = 0.026) and higher rates of heart failure (p = 0.03). Killip class on admission correlated with heart failure at discharge. Conclusion: Overweight elderly MI patients had higher heart failure incidence, but shorter hospital stays, suggesting nutritional and physiological status † Presenting Undergrad Author; ‡ Contributing Undergrad Author; * Undergrad Acknowledgment may influence recovery and outcomes. Further investigation is warranted. Keywords: Body Mass Index; Myocardial Infarction; Clinical Outcomes

Source:

Purdue University / 2025

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Co-authors:

Cao Danh Vo